Research Paper Volume 15, Issue 24 pp 15161—15182
Reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of SAP30 on cell apoptosis, ROS and MDA production in cerebral ischemic stroke
Figure 4. Identification of hub mRNAs and construction of SVM, RF and DT classification models. (A) LASSO regression analysis was performed on 26 intersection mRNAs; (B) Mean decreased accuracy sorting of SAP30, S100A12, CCR7, SLC2A3, JAK2, TLR4 and IL32; (C) Trend chart of AUC with the increase of DEmRNA quantity; (D) Correlation between SAP30, S100A12, CCR7, SLC2A3, JAK2 and TLR4. Red and blue represent positive and negative correlations, respectively. (E) Expression heatmap of SAP30, S100A12, CCR7, SLC2A3, JAK2 and TLR4; (F) ROC curve of SVM classification model in GSE58294 dataset; (G) ROC curve of RF classification model in GSE58294 dataset; (H) ROC curve of DT classification model in GSE58294 dataset.