Research Paper Volume 15, Issue 24 pp 15114—15133

Figure 2. (A) Expression of differential genes in GS-like group and GU-like group. The darker the red, the higher the expression level, and the darker the blue, the lower the expression level. (B) The display of differential genes in the volcano map: the top five most up-regulated lncRNAs and the top five most down-regulated lncRNAs were labeled respectively. The blue indicated down-regulated lnRNA, and the red indicated up-regulated lncRNAs. (C) The number of somatic mutations in GS-like group and Gu-like group was different (*** p <0.001). (D) The expression of UBQLN4 gene was different between the GS-like group and the Gu-like group (*** p <0.001). (E) The differentially expressed lncRNAs and the top 10 most related mRNAs formed a co-expression network, with yellow representing lncRNAs and green representing mRNAs. (F) GO enrichment analysis in GS-like group and GU-like group. The top five most significantly enriched functions were extracted from BP, CC and MF (p<0.05). (G) KEGG enrichment.