Research Paper Volume 15, Issue 24 pp 15084—15113

Figure 5. Immune profile of CMscore-based HCC groups. (A–C) Box and dot plot showing stromal score (A), immune score (B), and tumor purity of HCC patients from high- and low-CMscore subgroups. Wilcoxon test was used for data analyses. (D) Correlation analyses between CMscore and infiltration of 22 types of immune cells estimated by CIBERSORT method. (E) The box plot showing the enrichment score of 29 Fregs in HCC patients from the low- or high-CMscore subgroups. The “Angiogenesis Fibroblasts” related terms were marked with red font, the “Pro-tumor immune infiltrate” related terms were with yellow font, the “Anti-tumor immune infiltrate” related terms were with blue font, and “EMT signature / proliferation rate” related terms were with purple font. (F–K) Correlation analyses between CMscore and infiltration of 6 types of immune cells estimated by the TIMER website online. P-values were shown as *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.