Figure 5. Flowchart for the Mendelian randomization study. This chart illustrates the process used to determine the causal relationship between cognitive performance and site-specific fracture risk. SNP, single-nucleotide polymorphism; GWAS, genome-wide association study; MR, Mendelian Randomization; MR-PRESSO Mendelian Randomization Pleiotropy RESidual Sum and Outlier