Research Paper Volume 15, Issue 24 pp 14845—14863

Figure 1. The expression level of KIFC1 in pan-cancer. (A) KIFC1 expression levels in different cancers with TCGA combined with GTEx database. (B) A paired comparison analysis was conducted using the Mann-Whitney U test to analyze the expression differences of KIFC1 in the tumor and corresponding adjacent tissues. (C) KIFC1 expression levels in GSE26735, GSE62452 and GSE71729. (D) Genetic alteration landscape (Mutation, Structural Variant, Amplification, and Deep Deletion) of KIFC1 in 30 different tumors based on the TCGA database through the cBioPortal tool. (E) Prognosis of DFS between KIFC1 altered and unaltered groups. (F) Prognosis of PFS between KIFC1 altered and unaltered groups. (G) The immunofluorescence images of the KIFC1 protein, nucleus, endoplasmic reticulum (ER), microtubules, and the merged images in Hela and U251 cell lines. (H) The protein-protein interaction (PPI) network presents the proteins interacting with KIFC1 ns p ≥ 0.05; ^*p < 0.05; ^**p < 0.01; ^***p < 0.001. ^****p < 0.0001.