Research Paper Volume 15, Issue 24 pp 14764—14790

Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

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Figure 10. (A) NP cells were treated with different concentrations (50, 100 μM) of TBHP after 24 h and imaged by phase-contrast microscopy. (B) Cellular viability of the NP cells with different concentration of TBHP for 24 h. (C) Cellular viability of the TBHP-induced (100 μM) NP cells with different concentration of ZINC000072131515. (D, E) The protein expression of JAK3 in NP cells treated with different concentrations of ZINC000072131515. (F) NP cells migration was determined by scratch experiments, the results were recorded at 0, 24 h. (G) Percentage of wound closure of NP cells at 24 h. *P < 0.05; **P < 0.01; ***P < 0.0001; ns, non-significance.