Research Paper Volume 15, Issue 24 pp 14764—14790

Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

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Figure 1. (A) Sample clustering analysis to detect the outliers. (B) Determination of soft threshold power value. Left panel indicated scale-free model fit index; right panel indicated the mean connectivity of these values. (C) Dendrogram branch plot of genes based on dissimilarity measure and assignment modules. (D) Module-trait correlation heatmap between different clinical traits and modules. (E) Gene significance histogram plot of all clustered modules. (F) Eigenvalue correlation heatmap of the modules and clinical traits. (G) Correlation scatter plot between gene-significance and module membership.