Research Paper Volume 16, Issue 3 pp 2061—2076
LncRNA MEG3 inhibits the proliferation and migration abilities of colorectal cancer cells by competitively suppressing MiR-31 and reducing the binding of MiR-31 to target gene SFRP1
Figure 3. miR-31 can affect the expression of MEG3 in CRC cells and promote the proliferation of CRC cells. (A) dual luciferase assay results; (B) RT-qPCR detected the expression of miR-31 and MEG3 in each group; (C) Relative protein expression of SFRP1 and Ki-67 in each group; (D) CCK8 detected the proliferation of SW620 and SW480 cells. **P<0.01.