Research Paper Volume 15, Issue 24 pp 14720—14732
Meteorin-like protein elevation post-exercise improved vascular inflammation among coronary artery disease patients by downregulating NLRP3 inflammasome activity
Figure 3. Moderate-intensity continuous training (MICT) exercise was associated with increased plasma Metrnl and reduced inflammation. (A) Plasma Metrnl levels increased among CAD patients who underwent the 12-week MICT exercise period (CAD+Ex), compared to those who did not (CAD group). Exercise was inversely associated with (B) IL-1β, (C) TNF-α, and (D) CRP levels. (E) Plasma Metrnl levels increased among mice who underwent the 12-week exercise period, compared to those who remained sedentary. (F) Immunofluorescence staining for Metrnl in skeletal muscle from sedentary and exercise mice groups. Results are shown as mean ± SD. N =5/group. * P<0.05 was statistically significant.