Research Paper Volume 15, Issue 24 pp 14677—14702
Identification and validation of necroptosis-related gene signatures to predict clinical outcomes and therapeutic responses in acute myeloid leukemia
Figure 6. Construction of a necroptosis score and its clinical relevance. (A) Alluvial plot depicting subtype distributions in groups with different necroptosis clusters, gene clusters, necroptosis score, and overall survival. (B) Differences in the necroptosis score between three necroptosis clusters. (C) Differences in the necroptosis score between three gene clusters. (D) Kaplan–Meier survival analysis of groups with a high necroptosis score or low necroptosis score (P < 0.001, log-rank test). (E) Multivariate Cox regression analyses of the overall survival of AML patients. (F, G) “Waterfall” plot of somatic mutation features in groups with the high necroptosis score (F) or low necroptosis score (G).