Research Paper Volume 15, Issue 24 pp 14666—14676

Phoenixin-20 ameliorates Sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of the PKA/CREB signaling

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Figure 5. Phoenixin-20 repressed the release of inflammatory cytokines in the hippocampus tissue of Sev-treated rats. (A) mRNA level of IL-1β, IL-6, and MCP-1. (B) Protein level of IL-1β (pg/mL), IL-6 (pg/mL), and MCP-1 (pg/mL) (n=6, *, **, P<0.05 or 0.01 vs. sham group; †, ††, P<0.05 or 0.01, vs. Sev group).