Research Paper Volume 15, Issue 24 pp 14617—14650
Integrated analysis and validation of the TRIM28-H2AX-CDK4 diagnostic model assists to predict the progression of HCC
Figure 5. Diagnostic and prognostic values of TRIM28, H2AX and CDK4 expression in HCC. (A) The AUC for ROC curves for TRIM28, H2AX and CDK4 in normal liver tissues and HCC tissues, subgroup analysis for T1 stage, T2/T3/T4 stage, Pathologic stage I and Pathologic stage II/III/IV were computed. (B) Nomogram for predicting probability of patients with 1-, 3- and 5-year OS, DSS, PFS in entire TCGA cohort in HCC. Calibration curves of nomogram on consistency between predicted and observed 1-, 3-, and 5-year survival in entire TCGA cohort. Dashed line at 45° implicated a perfect prediction, and the actual performances of our nomogram were shown in blue lines.