Research Paper Volume 15, Issue 18 pp 9877—9889

Myeloid-specific knockout of SHP2 regulates PI3K/PLCγ signaling pathway to protect against early myocardial infarction injury

class="figure-viewer-img"

Figure 8. Myeloid-specific knockout SHP2 mediates the PI3K/PLCγ signaling pathway, affects the expression of inflammatory factors and the level of phagocytic activity, thereby promoting the phagocytic activity of macrophages and reducing the content of inflammatory factors, thereby protecting early myocardial infarction injury.