Research Paper Volume 15, Issue 16 pp 8471—8486

Tumor-derived exosomes RNA expression profiling identifies the prognosis, immune characteristics, and treatment in HR+/HER2-breast cancer

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Figure 6. The expression of risk model genes. (A) MTHFD2 mRNA expression levels in exosomes from MCF10A and MCF-7 cell line; (B) PDPK1 mRNA expression levels in exosomes from MCF10A and MCF-7 cell line; (C) PIR mRNA expression levels in exosomes from MCF10A and MCF-7 cell line; (D) WSB2 mRNA expression levels in exosomes from MCF10A and MCF-7 cell line, * p < 0.05, ** p < 0.01, *** p < 0.001. MTHFD2, methylenetetrahydrofolate dehydrogenase 2; PDPK1, phosphoinositide-dependent protein kinase 1; PIR, pirin; WSB2, WD repeat, and SOCS box containing 2.