Research Paper Volume 15, Issue 16 pp 8433—8443
Catapol reduced the cognitive and mood dysfunctions in post-stroke depression mice via promoting PI3K-mediated adult neurogenesis
Figure 3. Catapol perform the behavioral effects in PSD model in dependent with hippocampal neurogenesis. (A) Timeline of the injection procedure of TMZ administration alongside with the drug treatment. (B) Statistical analysis on the grooming time in splash test for pre-TMZ treatment. One-way ANOVA, Tukey’s post-hoc, ***: p<0.001. (C) Statistical analysis on the recognition index in ORT in pre-TMZ treatment. One-way ANOVA, Tukey’s post-hoc, ***: p<0.001. (D) Statistical analysis on the grooming time in splash test for post-TMZ treatment. One-way ANOVA, Tukey’s post-hoc, **: p<0.01. (E) Statistical analysis on the recognition index in ORT in post-TMZ treatment. One-way ANOVA, Tukey’s post-hoc, ***: p<0.001.