Figure 4. Homology modeling and molecular docking. The crystal structure and evaluation of (A) HIF1A and (B) PQKCQ. The ramachandran plot of (C) HIF1A structure. The ramachandran plot of (D) PQKCQ structure. The LDDT score of (E) HIF1A structure. The LDDT score of (F) PQKCQ structure. The assessment of protein conservation of HIF1A and PQKCQ was exhibited in (G, H) respectively. The best docking position between (I, J) ML228 and HIF1A or (K, L) staurosporine and PRKCQ were indicated. The absolute value of affinity between predicated small molecules and (M) HIF1A or (N) PQKCQ was shown.