Research Paper Volume 15, Issue 16 pp 8155—8184

Identified RP2 as a prognostic biomarker for glioma, facilitating glioma pathogenesis mainly via regulating tumor immunity

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Figure 9. Macrophage dynamics in glioma progression. (A, B) Quality control removal of low-quality cells (C) tSNE cell cluster analysis differentiating cell types in the tumor microenvironment. (D) Tumor cells were divided into 13 clusters showing RP2 expression sites in the tumor microenvironment. (E) Cell reclustering was performed by UAMP method, and macrophage types were analyzed. (F) expression of RP2 was shown in the reclustering cells. (G) Evolutionary tracks of all kinds of cells after dimension reduction (H) expression of RP2 changes with pseudo time (I) differentiation tracks of macrophages in glioma, with cluster color code.