Research Paper Volume 15, Issue 16 pp 8113—8136

Figure 4. Identification of pyroptosis phenotype-related gene signatures in the gastric cancer meta-cohort. (A) Venn diagram showing the overlapped pyroptosis phenotype-related DEGs among three pyroptosis phenotypes. (B, C) GO and KEGG enrichment results of the overlapped pyroptosis phenotype-related DEGs. (D) Heat map showing the optimal clustering by k = 3 based on the overlapped pyroptosis phenotype-related DEGs. (E) The CDF for the cumulative distributive function of the consensus matrix for k = 2–9 identified by different colors. (F) The CDF plots of consensus clustering matrix for k = 2–9. (G) The t-SNE plots of the mRNA expression of pyroptosis phenotype-related gene signatures visualizing three distinct pyroptosis genomic phenotypes. (H) Heatmap showing the differences in the expression of pyroptosis phenotype-related gene signatures and clinicopathological characteristics among three pyroptosis genomic phenotypes.