Research Paper Volume 15, Issue 16 pp 8044—8060

The alleviating effect and mechanism of GLP-1 on ulcerative colitis

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Figure 4. GLP-1 restores the intestinal barrier function in DSS-induced colitic mice. The protein levels of ZO-1 (A) and Occludin (B) were analyzed by immunofluorescence in the colon tissue. The protein expression of ZO-1 (C, D) and Occludin (C, E) were analyzed by western blotting. Data are presented as mean ± SD (n = 6 per group). For GLP-1-DSS vs. DSS group, *p < 0.05 - **p < 0.01 and for DSS vs. NT group, #p < 0.05 were considered significant.