Research Paper Volume 15, Issue 15 pp 7673—7688
Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression
Figure 8. Emodin treatment attenuated renal damage in STZ induced animal model. The blood glucose and body weight were determined at different time (A, B). The urine volume, urinary albumin, serum creatinine and ACR were monitored at 0 and 12 weeks (C–F). The protective mechanism of Emodin against DKD through inhibiting ferroptosis via regulating Nrf2 pathway (G). *p < 0.05, **p < 0.01 vs. NC group, vs. DM group.