Research Paper Volume 15, Issue 16 pp 7974—7996

Figure 4. The correlation and prognostic analysis of CXCL13 and CD8 exhausted cells (A). The KM analysis (A-1) of CXCL13 in the KIRC dataset, (A-2) of CXCL13 and CD8+ T cell percentage combined. The correlation between CXCL13 and markers of CD8 exhausted cell (A-3). The correlation and prognostic value of CXCL9/10 and macrophage M1 cells (B). The correlation between CXCL9/10 and three types of macrophage cells (B-1), and the forest plot (B-2) showing CXCL9/10 expression level and the percentages of three types of macrophage cells in the KIRC dataset. The variance analysis (B-3) of three types of macrophage cells between immunotherapy response and non-response groups. The correlation and prognostic value of CXCL genes and neutrophil (C). The correlations (C-1) among CXCL genes, CXCR1/2, and the percentage of neutrophil in two datasets, as well as the correlation (C-2) between CXCL genes and CXCR1/2. The KM analysis (C-3) for the percentage of neutrophil in the KIRC dataset (P = 0.03), and the KM analysis (C-4) for the percentage of neutrophil in the CM dataset (P = 0.83).