Research Paper Volume 15, Issue 15 pp 7533—7550

HBx promotes hepatocellular carcinoma progression by repressing the transcription level of miR-187-5p

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Figure 3. miR-187-5p inhibited proliferation, migration and invasion of hepatoma cells. (A) The transfection efficiency of miR-187-5p mimics and inhibitors was tested by RT-qPCR. (B, C) miR-187-5p mimics inhibited cell proliferation while miR-187-5p promoted cell proliferation by CCK-8 assays and EdU assays. (D, E) The effects of miR-187-5p mimics and inhibitors on migration and invasion of Huh-7 cell by Wound-healing and Transwell assays. The experiments were repeated at least 3 independent times. (BE) Data was presented as mean ± SD from three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.