Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation

Haitao Yang; Xiao Feng; Xiangdong Tong

doi:doi:10.18632/aging.204639

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Research Paper Volume 15, Issue 7 pp 2689—2704

Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation

Figure 3. POU6F2-AS2 upregulation promotes the aggressiveness of NSCLC cells. (A) The transfection efficiency of pc-POU6F2-AS2 in SK-MES-1 cells. ^**P < 0.001 vs. pcDNA3.1 group. (B and C) The proliferation and colony formation of POU6F2-AS2-overexpressed SK-MES-1 cells. ^*P < 0.01 vs. pcDNA3.1 group. ^**P < 0.001 vs. pcDNA3.1 group. (D and E) The motility of SK-MES-1 cells after POU6F2-AS2 upregulation. ^**P < 0.001 vs. pcDNA3.1 group.