Research Paper Volume 15, Issue 6 pp 2321—2346
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing’s sarcoma
Figure 2. ANXA1 expression in different subgroups based on the GSE17679, GSE45544 and GSE73166 datasets. (A) In different age groups, the expression levels of the ANXA1 gene were higher in the ≤ 20-year-old group than in the > 20-year-old group (P = 0.018). (B) In different gender groups, the expression levels of ANXA1 gene were not significantly different (P = 0.067). (C) In different type groups, the expression levels of the ANXA1 gene were higher in the primary group than in the metastasis group (P = 0.0072), and there was no significant difference between the remaining groups. (D) 22 ES samples from the GSE45544 and GSE73166 datasets validated that the expression levels of the ANXA1 gene were higher in the primary group than in the metastasis group.