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Research Paper Volume 15, Issue 6 pp 2097—2114

ADAMTS1 induces epithelial-mesenchymal transition pathway in non-small cell lung cancer by regulating TGF-β

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Figure 9. Effects of KTFP on migration, invasion, and EMT of the NSCLC A549 and H226 cell line. (A) Wound-healing showed the migration of A549 cells after adding KTFR. (B) Transwell assays showed the migration and invasion of A549 cells decreased after adding KTFR (scale bar=50 μm). (C) Protein expressions of E-cadherin, N-cadherin, and Vimentin in A549 cells were detected using Western blot analysis. (D) Wound-healing showed the migration of H226 cells was decreased after adding KTFR. (E) Transwell assays showed the migration and invasion of H226 cells were decreased after adding KTFR (scale bar=50 μm). (F) Protein expressions of E-cadherin, N-cadherin, and Vimentin in H226 cells were detected using Western blot. *P<0.05, **P<0.01, ***P<0.001 compared with NC group. N=3.