Research Paper Volume 15, Issue 6 pp 2082—2096

Single cell sequencing analysis constructed the N7-methylguanosine (m7G)-related prognostic signature in uveal melanoma

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Figure 8. The function of PAG1 in UVM cell line was verified by cell assay. (A) Knockdown efficiency of PAG1 gene. The knockdown efficiency of si-PAG1-2 group was the highest. (B) Clone formation experiment. The proliferation ability of MUM-2B and OCM-1 cell lines decreased significantly after PAG-1 knockdown. (C) EdU assay. (D) Transwell experiment. The migration and invasion ability of MuM-2B cell lines and OCM-1 cell lines were significantly reduced after PAG-1 knockdown. (E) Wound healing experiment.