Figure 4. Analysis of SHCBP1 alteration in pan-cancer. (A) The histogram showed alteration frequency of SHCBP1 mutation types in cBioPortal database. (B) Summary of structural variation, mutations and copy number alterations of SHCBP1. (C) The mutation site with the highest alteration frequency (R325H/C) in SHCBP1. (D) The correlation between alteration status and prognosis in COAD, HNSC and PRAD patients.