Research Paper Volume 15, Issue 5 pp 1668—1684

Figure 5. The differential expression of NMU in tumor and normal tissues. (A) Differential expression of NMU in tumor and normal tissues in the TCGA database (p = 1.4e-10). (B) Pair analysis of NMU expression between tumor and normal tissues from the same patient in the TCGA database (p = 2e-16). (C) The AUC of NMU expression was 0.854, obtained by a ROC curve analysis, distinguishing normal tissues from tumor tissues. (D) K-M analysis showed that patient prognosis was significantly worse when NMU expression was elevated (p = 0.047). (E) NMU was significantly overexpressed in tumor tissues, with a positive rate of 72% (18/25). (F) Serum NMU protein levels were significantly higher than in healthy individuals (^**p < 0.01). (G) RT-qPCR confirmed that NMU expression was significantly increased in tumor tissues (^*p < 0.05).