Figure 1. Analysis of DEGs and enrichment in PTC and normal thyroid samples. (A, B) Volcano plots of DEGs of TCGA-THCA and GSE54958 datasets. (C, D) Venn diagram of down- and up-regulated genes in TCGA and GSE54958 showed that 135 genes were down-regulated and 274 genes were upregulated. (E) DEGs were predominantly enriched in estrogen response-related pathways.