Research Paper Volume 15, Issue 5 pp 1371—1393
Identification of m6A regulator-mediated RNA methylation modification patterns and key immune-related genes involved in atrial fibrillation
Figure 4. Identification of three distinct m6A modification pattern subtypes in atrial fibrillation. (A) Consensus clustering cumulative distribution function (CDF) for k = 2-9. (B) Relative change in the area under the CDF curve for k = 2-9. (C) Heatmap of the matrix of cooccurrence proportions for atrial fibrillation samples. (D) Principal component analysis for the transcriptome profiles of three m6A clusters, showing a remarkable difference in the transcriptome between different modification patterns.