Research Paper Volume 15, Issue 4 pp 1039—1051

RIOK3 promotes mTORC1 activation by facilitating SLC7A2-mediated arginine uptake in pancreatic ductal adenocarcinoma

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Figure 4. RIOK3 promotes invasion and migration of PDAC cells via SLC7A2. (A, B) The invasion (A) and migration (B) abilities of the above cell lines in E were determined using the migration and invasion assays, respectively. One-way ANOVA test. All experiments were performed independently at least three times. The star (*) symbol denotes the level of statistical significance: * p < 0.05, ** p < 0.01, *** p < 0.001, ns no significance.