Research Paper Volume 15, Issue 4 pp 1025—1038

Figure 1. Circ_0001052 promoted hypertrophic effects. (A) The mRNA and protein levels of hypertrophic biomarkers in TAC and sham group. (B and C) The mRNA and protein levels of hypertrophic biomarkers in CMs. (D) The surface area of CMs by using IF staining. (E and F) The levels of circ_0009139, circ_0009140 and circ_0001052 in CMs. (G) The depletion efficiency of circ_0001052 in Ang II-treated CMs. (H) IF assay detected cell surface area under the knockdown of circ_0001052. (I and J). The mRNA and protein levels of hypertrophic biomarkers in Ang II-treated CMs with inhibited circ_0001052. ^**P < 0.01. Abbreviation: n.s: no significance.