Research Paper Volume 15, Issue 2 pp 553—566

Alterations of mesenchymal stem cells on regulating Th17 and Treg differentiation in severe aplastic anemia

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Figure 3. Assessment of Th17 activation after 5-days Th17 differentiation. (A) Activation of Th17 cells was confirmed by intracellular staining for IL-17 with flow cytometry. (B) The percentage of IL-17-secreting cells were lower in the control group, compared to the basic group (6.6 ± 0.4% vs 12.9 ± 1.2%, P < 0.01). The percentage of IL-17-secreting cells were significant higher in the SAA group, compared to the control group (9.1 ± 1.5% vs 6.6 ± 0.4%, P < 0.01). Data are presented as the mean ± SD. n = 5 in each group.