Research Paper Volume 15, Issue 2 pp 553—566

Alterations of mesenchymal stem cells on regulating Th17 and Treg differentiation in severe aplastic anemia

class="figure-viewer-img"

Figure 2. IL-17 and IL-1β concentrations in the culture supernatant after 5-days Th17 differentiation induction. IL-17 and IL-1β levels were lower when CD4+ T cells cocultured with control MSCs. The inhibitory effects were significantly decreased when cocultured with SAA MSCs. Data are presented as the mean ± SD. n = 5 in each group.