Research Paper Volume 15, Issue 4 pp 982—1003

Identification of cellular heterogeneity and key signaling pathways associated with vascular remodeling and calcification in young and old primate aortas based on single-cell analysis

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Figure 6. EGF signaling in young and old group. (A) Signaling changes of SMC1 and SMC2. (B) Circle plot of EGF signaling network in young and old group. (C) The communication probability of all the significant ligand-receptor pairs that contributed to EGF signaling. (D) Circle plot of BTC-EGFR ligand-receptor pairs in young and old group. (E) The expression of genes of EGF signaling pathway in each subpopulation and group. (F) The expression of EGFR in young and old group.