Figure 5. Overall signaling patterns and inferred signaling pathways. (A) Overall signal strength of each signaling pathway in each cell population. (B) Circle plot of PDGF signaling network in young and old group. (C) Circle plot of NOTCH signaling network in young and old group. (D) Circle plot of FN1 signaling network in young and old group. (E) Circle plot of BMP signaling network in young and old group.