Research Paper Volume 15, Issue 2 pp 308—352
Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice
Figure 8. Long-term voluntary wheel running reduced aging-induced loss of dendrite numbers in the 22 mo HBW mice. 10 mo endurance exercise reduced advanced aging-induced loss of dendrite numbers in the 22 mo HBW/VWR. (A) The effect of advanced aging on osteocyte dendrite number in two different subgroups, LBW and HBW mice. *: p < 0.05, 22 mo vs. 18 mo mice. (B) The effect of VWR on osteocyte dendrite number in two different subgroups, LBW and HBW mice. **: p < 0.01, VWR vs. CTRL mice. Abbreviations: CTRL: control group; VWR: voluntary wheel running group; CBW: Combined groups (18 mo: n = 16 CTRL, n = 15 VWR; 22 mo: n = 8 CTRL, n = 8 VWR); LBW: Low body weight group (18 mo: n = 8 CTRL, n = 8 VWR; 22 mo: n = 4 CTRL, n = 4 VWR); HBW: High body weight group (18 mo: n = 8 CTRL, n = 7 VWR; 22 mo: n = 4 CTRL, n = 4 VWR).