Research Paper Volume 15, Issue 2 pp 308—352
Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice
Figure 5. Body weight effects on soleus and EDL skeletal muscle weights and contractile force. (A) Soleus muscle weight (left) and muscle weight/body weight (MW/BW) ratio (right), (B) absolute maximal contractile force (left) and specific maximal contractile force (right), (C) absolute submaximal contractile force (left) and specific submaximal contractile force (right) in LBW and HBW mice. (D) EDL muscle weight (left) and muscle weight/body weight (MW/BW) ratio (right), (E) absolute maximal contractile force (left) and specific maximal contractile force (right), (F) absolute submaximal contractile force (left) and specific submaximal contractile force (right) in LBW and HBW mice. *: p < 0.05, **: p < 0.01, ***: p < 0.001 and ****: p < 0.0001. VWR vs. CTRL mice. Abbreviations: CTRL: control group; VWR: voluntary wheel running group; LBW: Low body weight group (18 mo: n = 8 CTRL, n = 10 VWR; 22 mo: n = 4 CTRL, n = 4 VWR); HBW: High body weight group (18 mo: n = 8 CTRL, n = 7 VWR; 22 mo: n = 4 CTRL, n = 4 VWR).