Research Paper Volume 14, Issue 19 pp 8077—8094
Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets
Figure 2. 2JY-OBZ4 resisted tau hyperphosphorylation in HEK293-hTau cells transfected with GSK-3β plasmid. (A) Western blots and (B–D) quantitative analysis for GSK-3β, Tau, tau-pT181 and tau-pS396 in HEK293-hTau cells overexpressed with GSK-3β. MW Molecular weight. n = 3 per group. NS means no significance, p value significance is calculated from a one-way ANOVA, data are represented as mean ± SEM. *p < 0.05 and ##p < 0.01.