Research Paper Volume 14, Issue 19 pp 7972—7985
DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway
Figure 6. Abnormal alternative splicing of KITLG activates the ERK signaling pathway. (A and B) Agarose gel electrophoresis demonstrated the transfer efficiency on different isoforms of KITLG in both HEK293 and MM cells. (C and D) WB test verified that phosphorylated ERK expression was enhanced in KITLG isoform1-OE cells and downregulated in KITLG isoform2-OE cells.