Research Paper Volume 14, Issue 19 pp 7959—7971
APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6
Figure 5. Transcriptome analysis of sh-APEX1-treated HCC cells. (A) The heat map of DEGs between sh-APEX1 and sh-Ctrl HCC cells. (B, C) GO (B) and KEGG signaling pathway (C) analyses of DEGs. (D) Protein interaction network analysis of DGEs. (E) Expression of MAP2K6, TNFAIP3, and CASP3, which are enriched in the TNF signaling pathway, were confirmed by qRT-PCR. **P < 0.01.