Figure 4. APEX1 promotes tumor growth in vivo. (A) An in vivo tumorigenesis model was established, and tumor volumes were measured every 7 days. (B) Tumors were exercised from mice and photographed. Tumor weight was determined. (C) APEX1 expression in isolated tumors was evaluated by immunohistochemistry. (D) The establishment of the orthotopic liver cancer model and numbers of tumor nodules was evaluated. *P < 0.05.