Research Paper Volume 14, Issue 17 pp 7170—7185

A circadian rhythm-related gene signature for predicting relapse risk and immunotherapeutic effect in prostate adenocarcinoma

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Figure 7. Association of the CR-related gene signature with tumor infiltrating immune cells in PRAD. (A) Comparison of tumor infiltrating immune cells between low- and high-risk groups demonstrated that there existed a significant difference in the abundance of B cell naive, B cell plasm, T cell CD4 memory, T cell follicular helper, and monocyte (P < 0.05). (BD) Risk score was inversely correlated with B cell naive, B cell plasm, T cell CD4 memory, T cell follicular helper, and monocyte (R < 0, P < 0.05). (E) Risk score was positively correlated with T cell CD4 memory (R < 0, P < 0.05). (F) Risk score was inversely correlated with monocyte (R < 0, P < 0.05).