Research Paper Volume 14, Issue 17 pp 7170—7185
A circadian rhythm-related gene signature for predicting relapse risk and immunotherapeutic effect in prostate adenocarcinoma
Figure 4. Comparison of the CR-related gene signature with other indicators for RFS in PRAD. (A) CR-related gene signature showed an improved predictive performance than other clinical indicators, with an AUC of 0.831. (B) CR-related gene signature (Signature 1) showed an improved predictive performance than other four reported gene signatures. (C) CR-related gene signature also showed an ideal predictive performance in an independent cohort of PRAD (GSE70768), with an AUC of 0.944. (D) Low-risk group had an improved RFS than high-risk group in an independent cohort of PRAD (GSE70768) (with a cutoff point of median value; log-rank test, P = 0.003).