Research Paper Volume 14, Issue 18 pp 7300—7327
Age-related metabolic and neurodegenerative changes in SAMP8 mice
Figure 10. Increased activation of tau kinase GSK-3β and decreased activation of protein phosphatase 2A sub C in the hippocampi of SAMP8 (A) western blots and (B) their quantification. Data are mean ± SEM, analyzed by 2-way ANOVA with Bonferroni post test. Significance is *P < 0.05, **P < 0.01 and ***P < 0.001; * SAMP8 compared to SAMR1, + age-dependent changes in SAMR1, and # age-dependent changes in SAMP8. n = 4-5 mice per group.