Research Paper Volume 14, Issue 17 pp 7065—7092

The general law of plasma proteome alterations occurring in the lifetime of Chinese individuals reveals the importance of immunity

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Figure 4. The expression of hub genes and transcription factor (TF) regulatory network in the critical module. (A) The expression heatmap of hub gene. (B) The interaction regulatory network of TF and target genes. The core circles are two transcription factors (CDC5L and HMGB2). The surrounding circles represent their target genes, the color represents the source module, the circle size represents the expression, and the yellow circle represents the hub gene.