Figure 1. Network construction of the weighted co-expressed genes and their associations with age. (A) The Group hierarchical clustering tree. (B) Determination of soft-thresholding power. (C) The heatmap of genes correlation in modules. (D) Hierarchical clustering dendrograms (HCD) of modules. HCD using dynamic tree cut, depicting 14 plasma protein modules. Each branch of the HCD presents a single protein, and the colored bar below refers to its corresponding protein module. The HCD height is the distance between proteins.