Research Paper Volume 14, Issue 17 pp 6859—6886

Figure 2. Volcano plot of plasma miRNAs associated with baseline MMSE score. Estimates (pooled from ten imputed datasets) from linear models adjusted for age, education, alcohol consumption, and smoking status. The 5 and 6 most statistically significant extracellular miRNAs with negative and positive beta estimates, respectively, are labeled. The 2 extracellular miRNAs significant at FDR q-value < 0.05 are plotted in red. Abbreviations: FDR: False Discovery Rate; MMSE: Mini-Mental State Examination; n.s.: not significant.