Figure 2.Volcano plot of plasma miRNAs associated with baseline MMSE score. Estimates (pooled from ten imputed datasets) from linear models adjusted for age, education, alcohol consumption, and smoking status. The 5 and 6 most statistically significant extracellular miRNAs with negative and positive beta estimates, respectively, are labeled. The 2 extracellular miRNAs significant at FDR q-value < 0.05 are plotted in red. Abbreviations: FDR: False Discovery Rate; MMSE: Mini-Mental State Examination; n.s.: not significant.
