Research Paper Volume 14, Issue 17 pp 7003—7013

UBE2C mediated radiotherapy resistance of head and neck squamous cell carcinoma by regulating oxidative-stress-relative apoptosis

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Figure 4. Silencing UBE2C sensitized CAL27 to radiation in vivo. (A) Representative images of subcutaneous tumors after treatment. The curves describe the average tumor volume in vivo of four different groups at different observing time. (B) Representative images of tumors from xenografts using immunohistochemical staining against Ki67. Magnification: ×200. (C) The percentage of TUNEL-positive cells was assessed in formalin-fixed paraffin embedding sections of tumors in each group. Magnification: ×200. *P < 0.05, **P < 0.01, ***P < 0.001 versus the control.