Research Paper Volume 14, Issue 17 pp 6993—7002
Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways
Figure 5. Effect of Phps on APAP-induced acute liver injury were dependent on Nrf2. The mice were received Phps (80 mg/kg) prior 1h APAP (500 mg/kg) injection and liver was collected for Western blot. (A, B) are protein bands of Nrf2 signaling pathway; (C–F) represent the ratio of HO-1, GCLC, GCLM and NQO1protein to β-actin. All data are presented as mean ± SD (three independent experiments). #p < 0.05 and ##p < 0.01 vs. control group; *p < 0.05 and **p < 0.01 vs. APAP group.